Phenobarbital

CAS Number: 50-06-6
Formula: C12H12N2O3
Formula Weight: 232.24 g/mol
Appearance (Color) White
Appearance (Form) Powder
Solubility (Color) Colorless
Solubility (Turbidity) Clear
50 mg/mL, EtOH
Infrared spectrum Conforms to Structure
Purity (Titration by NaOH) > 99 % _
Purity (TLC) > 99 % _

Description

Phenobarbital

Phenobarbital, also known as phenobarbitone or phenobarb, is a medication recommended for the treatment of certain types of epilepsy in developing countries In the developed world it is commonly used to treat seizures in young children, while other medications are generally used in older children and adults. It may be used intravenously, injected into a muscle, or taken by mouth. The injectable form may be used to treat status epilepticus. It is occasionally used to treat trouble sleeping, anxiety, and drug withdrawal and to help with surgery.

Medical uses
It is used in the treatment of all types of seizures except absence seizures. It is no less effective at seizure control than phenytoin, however phenobarbital is not as well tolerated. It may provide a clinical advantage over carbamazepine for treating partial onset seizures. Carbamazepine may provide a clinical advantage over phenobarbital for generalized onset tonic-clonic seizures.

It  is the first-line choice for the treatment of neonatal seizures.

It is sometimes used for alcohol detoxification and benzodiazepine detoxification for its sedative and anticonvulsant properties. The benzodiazepines chlordiazepoxide (Librium) and oxazepam (Serax) have largely replaced phenobarbital for detoxification.

It’s properties can effectively reduce tremors and seizures associated with abrupt withdrawal from benzodiazepines.

This product is intended for forensic and research applications.
This product has been manufactured and tested to meet ISO17025:2005 and Guide 34:2009 guidelines
This product is intended to be used as an analytical reference standard
Bulk material is available for academic research at qualified institutions; please contact our sales department for pricing